Magnetic resonance elastography (MRE) is a noninvasive imaging tool for the quantitative measurement of liver stiffness. MRE has a high accuracy for the diagnosis of liver fibrosis, independent of BMI or chronic liver disease etiology .
Several studies have characterized the diagnostic performance of MRE for the staging of liver fibrosis in chronic liver disease. These studies report a range of threshold values used for fibrosis staging (Table 1).
For example, the following values are used at the Mayo Clinic .
A pioneering European research project, designed to develop new diagnostic tests to assess patients with Non-Alcoholic Fatty Liver Disease (NAFLD) has expanded giving access to more patients.
Although many people have NAFLD, less than one in 10 will come to harm as a result. The challenge is to identify those people that will be most severely affected so that appropriate care can be targeted to those that need it most.
Incorporating several new partners also enables access to even more state-of-the art technologies.
Liver Investigation: Testing Marker Utility in Steatohepatitis (LITMUS) funded by the European Innovative Medicines Initiative 2 Joint undertaking, brings t...
Seeing the images from an MRE exam - called an elastogram - can be a significant moment for patients battling liver disease.
"Seeing my liver and the state of disease for the first time was a very powerful, emotional moment - it left me speechless," recalled Deb Sobel, who was diagnosed with Primary Biliary Cholangitis (PSC) in 1998.
"MRE painted a true picture of the PBC progression. I used to be mad at my liver, but then I felt bad for it and decided to protect and take care of it as much as possible."
While "seeing" liver fibrosis via MRE can often help patients understand their disease better, the actual stiffness value - expressed in kPa - can help determ...