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MR Elastography Evidence Library

[PLACEHOLDER TEXT] Multiple published studies have demonstrated that MRE has high diagnostic performance for detecting and staging liver fibrosis. In this role, it is a more comfortable, safer, and less expensive alternative to liver biopsy. We provide a large body  published studies that provide diagnostic performance data for MRE, using biopsy as the standard of truth (1-24). A metric of diagnostic performance that is listed in all of these studies is the “area under the ROC curve” (AUC).

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Liver Fibrosis: Noninvasive Assessment with MR Elastography versus Aspartate Aminotransferase-to-Platelet Ratio Index

2007

Radiology

Laurent Huwart, MD, Christine Sempoux, MD, PhD, Najat Salameh, MSc, Jacques Jamart, MD, Laurence Annet, MD, PhD, Ralph Sinkus, PhD, Frank Peeters, PhD, Leon C. ter Beek, PhD, Yves Horsmans, MD, PhD, and Bernard E. Van Beers, MD, PhD

DOI:

PMID:

Assessment of chronic hepatitis and fibrosis: comparison of MR elastography and diffusion-weighted imaging

2011

American Journal of Roentgenology

Wang Y, Ganger DR, Levitsky J, Sternick LA, McCarthy RJ, Chen ZE, Fasanati CW, Bolster B, Shah S, Zuehlsdorff S, Omary RA, Ehman RL, Miller FH

DOI:

PMID:

2016

JMRI

Fenstad ER

DOI:

PMID:

2015

Clin Gastro and Hepatology

Singh S

DOI:

PMID:

Liver

Resounding Innovation

Brain
  1. Singh, S., et al., Diagnostic performance of magnetic resonance elastography in staging liver     fibrosis: a systematic review and meta-analysis of individual participant data. Clinical Gastroenterology and Hepatology, 2015. 13: p. 440-451.
  2. Imajo, K., et al., Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography. Gastroenterology, 2016. 150: p. 626-637.
  3. Wang, Q.B., H. Zhu, and B. Zhang, Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis. Hepatology, 2012. 56: p. 239-247. 
Brain
Breast
  1. Singh, S., et al., Diagnostic performance of magnetic resonance elastography in staging liver     fibrosis: a systematic review and meta-analysis of individual participant data. Clinical Gastroenterology and Hepatology, 2015. 13: p. 440-451.
  2. Imajo, K., et al., Magnetic resonance imaging more accurately classifies steatosis and fibrosis in patients with nonalcoholic fatty liver disease than transient elastography. Gastroenterology, 2016. 150: p. 626-637.
  3. Wang, Q.B., H. Zhu, and B. Zhang, Performance of magnetic resonance elastography and diffusion-weighted imaging for the staging of hepatic fibrosis: a meta-analysis. Hepatology, 2012. 56: p. 239-247. 
Breast
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