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Total Liver Health in One Exam

Hepatology/GI
Fibrosis Staging

MR Elastography (MRE) measures stiffness by assessing four images across the entire liver, resulting in a comprehensive and incredibly accurate diagnosis not available with other non-invasive technologies. In addition to a stiffness score measured in kPa, clinicians and patients often receive color-coded maps of their liver fibrosis, called Elastograms.  In these intuitive maps, red corresponds to highly advanced fibrosis, while purple represents healthy liver tissue.

MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
MR Elastography versus Fibroscan
When to use MRE

MR Elastography is able to overcome many confounding factors that can impact the performance in other non-invasive technologies. Notably for fatty liver disease, this most often includes BMI and increased waist circumference, as ultrasound-based elastography (e.g., Fibroscan®) methods often perform poorly in these patient groups.

 

Because MRE is not affected by waist circumference or obesity, clinical guidelines recommend that MRE be incorporated into the clinical workflow to reliably estimate the degree of fibrosis present. Clinicians may also request fat fraction measurements (for steatosis), inflammation, and/or malignancy via traditional MR workup, resulting in a powerful and comprehensive liver assessment. 

BMI ≤ 20

BMI ≥ 25

BMI ≥ 30

MR Elastography versus Fibroscan

Clinical guidance suggests that the utilization of MR Elastography increases as BMI increases

MR Elastography for Liver Fibrosis Assessment
Resoundant, Inc

MR Elastography for Liver Fibrosis Assessment

Recommended in
Clinical Guidelines
AGA guidelines Elastography

“In adults with NAFLD and a higher risk of cirrhosis, MRE is suggested, rather than VCTE, for detection of cirrhosis”

 

American Gastroenterological Association Institute Guideline on the Role of Elastography in the Evaluation of Liver Fibrosis (2017)

AASLD guidelines Elastography

"MRE is excellent for identifying varying degrees of fibrosis in patients with NAFLD."

 

The Diagnosis and Management of Nonalcoholic Fatty Liver Disease: Practice Guidance From the American Association for the Study of Liver Diseases (2017)

ACR guidelines Elastography

"MR elastography is the most accurate method for diagnosing liver fibrosis non-invasively because it assesses the whole liver and can stage liver fibrosis."

 

American College of Radiology Appropriateness Criteria®: Chronic Liver Disease (2017)

MR Elastography verss Fibroscan