News & Updates

November 15, 2019

The following research appeared in the November issue of Hepatology Communications, and can be found at:

https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep4.1446

Multiparametric Magnetic Resonance Elastography Improves the Detection of NASH Regression Following Bariatric Surgery

Abstract:

Disease monitoring in nonalcoholic steatohepatitis (NASH) is limited by absence of noninvasive biomarkers of disease regression or progression. We aimed to examine the role of multiparametric three‐dimensional magnetic resonance elastography (3D‐MRE) and magnetic resonance imaging proton density fat fraction (MRI‐PDFF) in the detection of NASH regression after interventions....

November 8, 2019

The following poster was presented at The Liver Meeting® in early November 2019, hosted by the American Association for the Study of Liver Diseases (AASLD).  The research examined the success rate of MR Elastography exams in 1,056 patients with a mean body mass index (BMI) of 32.  The success rate of MRE in this patient population was 97%.  This important research continues to demonstrate that MRE can be a highly useful tool for diagnosing and staging liver fibrosis in patient populations were obesity is highly prevalent, such as non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).

LIVER STIFFNESS USING MR ELASTOGRAPH...

August 27, 2019

Richard L. Ehman, MD

Professor of Radiology Blanche R. & Richard J. Erlanger Professor of Medical Research Mayo Clinic President and CEO, Resoundant Inc.
 

Adapted from article produced by Medpace, Inc.: https://www.medpace.com/wp-content/uploads/2019/08/QA-with-Imaging-Expert-Dr.-Richard-Ehman.pdf


 

What are the specific biomarkers of liver disease that MRE is uniquely suited to provide for clinical trials in NASH?

NASH is typically described in histologic terms: increased fat in hepatocytes, inflammatory activity, cellular injury, and development of fibrosis. Among these processes, fibrosis is most strongly associated with mortality. Currently, the most important bioma...

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