News & Updates

Resoundant Joins LITMUS

Supported by the European Union with 34 million euro as part of the European Innovative Medicines Initiative, the LITMUS (Liver Investigation: Testing Marker Utility in Steatohepatitis) project brings together clinicians and scientists to develop new non-invasive diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD). The LITMUS project will run for 5 years, involving over 90 academic centers and companies across Europe and the US, and is coordinated by the University of Newcastle, in collaboration with Pfizer Ltd. "Resoundant looks forward to participating in this ground-breaking, multi-stakeholder project to help address one medicine’s greatest challenges of the

Fact Sheet: Liver Fat Does Not Affect Liver Stiffness Measured with MR Elastography

KEY TAKEAWAY The presence of liver fat does not reduce liver stiffness measured by MRE. Multiple published studies report that hepatic steatosis does not systematically affect MRE-measured liver stiffness in patients with chronic liver disease. MRE is recognized as the most reliable non-invasive diagnostic test for detecting and staging liver fibrosis. Note: for a printable PDF of this fact sheet, click here. Background MR elastography (MRE) has emerged as the most reliable non-invasive diagnostic technology for detecting and staging liver fibrosis [1-2]. Among the histologic processes associated with chronic liver disease (fibrosis, inflammation, steatosis, and cell injury), the presence an

MRE links liver stiffness, CVD risk in patients with type 2 diabetes

Increased liver fibrosis assessed by magnetic resonance elastography among patients with nonalcoholic fatty liver disease and type 2 diabetes correlated with a higher risk for cardiovascular risk, according to published data. “Accurately assessing [cardiovascular disease] risk in NAFLD patients is critical to improving clinical outcomes,” Neeraj Mangla, MD, from the NAFLD Research Center in La Jolla, California, and colleagues wrote. “Utilization of liver stiffness measurements to non-invasively assess for liver fibrosis is broadening and magnetic resonance elastography (MRE) is the most accurate modality in NAFLD.” To determine if MRE-assessed liver fibrosis stage is associated with CVD ri

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