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Hello from our new imaging core lab

Resoundant Expands Services Offerings to Support Use of Quantitative Imaging Biomarkers in Clinical Trials Kay Pepin, PhD is Manager, Research Translation for Resoundant. Since Resoundant’s founding in 2010, our goal has always been to develop and implement MR Elastography for clinical use.  As a highly accurate, non-invasive way to assess liver fibrosis, Mayo Clinic has embraced this patient-friendly approach to liver health, dramatically reducing the number of needle biopsies. Today, the hospital does over 1,350 MRE exams per year to stage liver fibrosis in patients. However, in recent years, the rising prevalence and awareness of NAFLD/NASH has led to a surge in drug development in this a

It’s official – we’re in the core lab business

Resoundant Expands Services Offerings to Support Use of Quantitative Imaging Biomarkers in Clinical Trials Resoundant, Inc. announced today that the company is expanding its clinical research services in collaboration with the scientists and medical professionals at Mayo Clinic. In recent years, clinical research to address chronic liver diseases, such as non-alcoholic steatohepatitis (NASH) and non-alcoholic fatty liver disease (NAFLD), has accelerated tremendously. Resoundant has been increasingly involved in advising and providing core lab services for numerous high-profile Phase IIa and Phase IIb trials in these areas. In response to this growing global demand, Resoundant has made signif

MRE Top Noninvasive Test for Confirming NASH Fibrosis

Abstract Background: There has been an increased interest in the use of noninvasive tests (NITs) to identify advanced liver fibrosis in patients with nonalcoholic fatty liver disease (NALFD). The aim of our study was to define the change in tests' characteristics (sensitivity and specificity) of different combinations of NITs to detect advanced fibrosis in NAFLD. Methods: We stratified NITs into first and second tiers and compared two different strategies of combining NITs to screen for advanced fibrosis in patients with NAFLD. One strategy was using NITs in parallel, and the other was using NITs sequentially. Within both of these strategies, there were two ways of interpreting the overall

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